The reference site for Risperidone

Risperidone, sold under the trade name Risperdal among others, is an antipsychotic medication.


Risperidone is an atypical antipsychotic medication. It is most often used to treat delusional psychosis (including schizophrenia).

This medication is also used to treat some forms of bipolar disorder and psychotic depression.

Risperidone works by changing the effects of chemicals in the brain. Some of the brand names of risperidone is the US are Belivon®, Rispen®, Risperdal®.


Brand Name(s): Risperdal
CAS nº: 106266-06-2
(ris per’ i done)


Product Info

The sections below will provide you with more specific information and guidelines related to risperidone and its correct use. Please read them carefully.

FDA Information

In December 2003, physicians treating patients with bipolar mania gained a new treatment option with the FDA-approval of risperidone (Risperdal®) used alone or in combination with lithium or valproate. The FDA approved risperidone for the short-term treatment of acute manic or mixed episodes associated with bipolar disorder.

Risperidone is now the most commonly prescribed antipsychotic medication in the United States.

However, risperidone has received a “not approved” letter from the FDA for use in autism.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Risperidone is used for the treatment of psychotic disorders, for example, schizophrenia. It also is used in combination with lithium or valproate for the treatment of acute manic or mixed episodes associated with bipolar I disorder.

This medication works by interfering with the communication among nerves in the brain. The nerves communicate with one another by producing and releasing chemicals called neurotransmitters. The neurotransmitters attach to receptors on other nearby nerves, and the attachment of the neurotransmitter causes changes in the cells that have the receptor on them. Risperidone blocks several of the receptors on nerves including dopamine type 2, serotonin type 2, and alpha 2 adrenergic receptors and this blocks communication among nerves.

Risperidone is a relatively new antipsychotic medication that probably has fewer side effects than many of the older medications.

Other uses for this medicine

Risperidone has also been used to treat severe behavioral problems in children and teenagers, as well as in the treatment of irritability associated with autistic disorders. However, it is important to note that the FDA has warned that the safety of risperidone in children has actually never been established.

Moreover, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition.

Dosage and using this medicine

Risperidone comes as a tablet, a solution (liquid), and an orally disintegrating tablet to take by mouth.

It is usually taken once or twice a day with or without food.

Take risperidone exactly as directed by your doctor. Do not take more or less of it or take it more often than prescribed by your doctor.

Use the dropper provided to measure your dose of risperidone oral solution. You can take the oral solution with water, orange juice, coffee, or low-fat milk. Do not take the solution with tea or cola.

To take the orally disintegrating tablet, use dry hands to separate one blister unit at the perforation. Peel back the foil and remove the tablet. Do not push the tablet through the foil. Immediately place the entire tablet on your tongue but do not chew it. The tablet will quickly dissolve and may be swallowed with or without water.

Additionally, your doctor will probably start you on a low dose of risperidone and gradually increase your dose every day for several days, and then not more than once every week.

Please note that risperidone controls schizophrenia but does not cure it. It may take several weeks or longer before you feel the full benefit of risperidone. Continue to take risperidone even if you feel well, and never take risperidone without first talking with your doctor. If you suddenly stop taking risperidone, your symptoms may return and your illness may become harder to treat.

What special precautions should I follow?


Tell your doctor if you suffer from the following symptoms: had a heart attack; low blood pressure; an irregular heart-beat; or any other type of heart disease; epilepsy or another seizure disorder (or a history of this); diabetes; ever been diagnosed with breast cancer; liver disease; or kidney disease.

You may not be able to take risperidone, or you may require a dosage adjustment or special monitoring during treatment, if you have any of the conditions listed above.

Elderly patients with dementia-related psychosis treated with risperidone are at an increased risk of death compared to placebo. Risperidone is not approved for the treatment of patients with Dementia-Related Psychosis. Talk to your doctor if you have any questions regarding the use of risperidone.

Moreover, despite that risperidone has been used to treat severe behavioral problems in children and teenagers, as well as in the treatment of irritability associated with autistic disorders, it is important to note that the FDA has warned that the safety of risperidone in children has actually never been established. If the patient is under 18 years of age, please consult with your doctor or local pharmacist about the possible side effects or alternatives that exist.

Hyperglycemia (increased blood sugar) has been reported in patients treated with atypical antipsychotics including risperidone. Talk to your doctor if you experience any signs of hyperglycemia including excessive thirst, frequent urination, excessive hunger or weakness.

The risperidone (Risperdal®) orally-disintegrating tablets contain phenylalanine. The 0.5 mg tablets contain 0.14 mg phenylalanine, the 1 mg tablets contain 0.28 mg phenylalanine, and the 2 mg tablets contain 0.5 mg phenylalanine. Individuals with phenylketonuria may need to monitor their intake of this additive.

Risperidone is in the FDA pregnancy category C. This means that it is not known whether risperidone will be harmful to an unborn baby. Do not take risperidone without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Additionally, it is not known whether risperidone passes into breast milk. Do not take risperidone without first talking to your doctor if you are breast-feeding a baby.

If you are over the age of 65, you may be more likely to experience side effects from risperidone. An increased risk of stroke and transient ischemic attack (TIA, “mini-stroke”) has been associated with the use of risperidone in elderly patients with dementia-related psychosis. Your doctor may prescribe a lower dose of the medication or special monitoring during treatment.

What should I do if I forget a dose?

Take the missed dose of risperidone as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed.

Please do not take a double dose of this medication to make up for a missed one.

What side effects can this medication cause?

Possible side effects from using risperidone may include:

low blood pressure
muscle stiffness
muscle pain
increased salivation
weight gain

Tell your doctor if any of these symptoms are severe or do not go away:

upset stomach
weight gain
stomach pain
increased dreaming
difficulty falling asleep or staying asleep
decreased sexual interest or ability
heavy bleeding during menstrual periods
runny nose
sore throat
muscle pain
dry or discolored skin
dry mouth
difficulty urinating

If you experience any of the following symptoms, call your doctor immediately:

muscle stiffness
fast or irregular pulse
unusual movements of your face or body that you cannot control
slow or difficult speech
weakness or numbness in an arm or leg
difficulty swallowing
slow movements or shuffling walk
shortness of breath
painful erection of the penis that lasts for hours

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Try to always keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Please remember to throw away any medication that is outdated or no longer needed. If required, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, please call the local emergency services immediately on 911.

Symptoms of a risperidone overdose may include:

rapid, pounding, or irregular heartbeat
upset stomach
blurred vision

Product Images


Below you will find images and specific information on the principal types of risperidone that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Strength(s): 0.5 MG
Imprint: Ris 0.5 | JANSSEN
Manufacturer: JANSSEN PHARM.

Strength(s): 1 MG
Imprint: JANSSEN | R 1
Manufacturer: JANSSEN PHARM.

Strength(s): 2 MG
Imprint: JANSSEN | R 2
Manufacturer: JANSSEN PHARM.

Strength(s): 3 MG
Imprint: JANSSEN | R 3
Manufacturer: JANSSEN PHARM.

Strength(s): 4 MG
Imprint: JANSSEN | R 4
Manufacturer: JANSSEN PHARM.

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